A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Spatial composition facilitates cooperation in a social dilemma: empirical evidence from a bacterial community
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I can hardly imagine how I, as a geneticist, would be able to master essential physics, let alone compete at the top. How did you go over it?
2010, produced a different way (‘wedging transfer’) to govern nanostructures; initial report of DNA translocation by way of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into good-state nanopores
Our investigate ranges in the biophysics of DNA to artificial cells and outside of. You should take a look under with the spectrum of our latest jobs.
We use nanofabricated microfluidic buildings to sample spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the basic position of spatial confinement with the molecular and mobile stage. Our jobs consist of the subsequent:
Dynamic ParB–DNA interactions initiate and manage a partition condensate for bacterial chromosome segregation
The rotors harness Power from a nanoscale h2o and ion move that is definitely created by a static chemical or electrochemical likely gradient within the nanopore, which are recognized by way of a salt gradient or used voltage, respectively. These artificial nanoengines self-organize and run autonomously in physiological situations, suggesting strategies to constructing Electrical power-transducing motors at nanoscale interfaces.
There was a single difficulty while — we didn't notice any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule stage, conducting polymers ended up essentially not these types of great conductors, which was rather disappointing. We Therefore broadened our see to try to locate much more promising molecules.
In 1993 he was appointed as Affiliate Professor at Delft College of Technology. While in the mid-nineteen nineties Dekker and his team attained results with the invention from the electronic Houses of carbon nanotubes, the main single-molecule transistor along with other nanoscience.
‘That considerations the artificial cell, as Section of the Dutch BaSyC initiative. Craig Venter appeared leading-down in those days and discovered about five hundred genes that happen to be minimally required for the functioning cell. We wish to glimpse bottom-up: how can we shift from a handful of molecules to an entire Organic method?
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
Solid-point out nanopores have proven to become a remarkably flexible probe for single-molecule analysis of DNA. I will describe some of our recent findings – specifically DNA knots – as well as our efforts to extend the abilities of stable-condition nanopores even even ceesdekker more, inside the course of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.